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KMID : 0367419790200010013
Journal of Korean Pediatric Society
1979 Volume.20 No. 1 p.13 ~ p.19
Clinical Review of Tuberculous Meningitis in Children
üÜéÌã°/Hwang, Yong Seung
ëÅñ£Ï´/ÍÔÎÃéð/Yun, Chong Koo/Ko, Kwang Wook
Abstract
The following results were obtained through the clinical review of 89 cases of tuberculous meningitis which were treated at the Department of Pediatrics of Seoul National University Hospital during the peroid of 3 years from June 1973 till May. 1976.
1. The highest incidence by age was noted as 80.996 under the age of 6 years and 24.7% of cases were between the age of 1 and 2 years, Male to female ration was 1.2: 1.
2. 35% of cases were noted in the spring, 28%, in the summer, 19%, in the autumn and 18% in the winter.
3. The chief complaints on admission were in the ¢¥order of vomiting, fever, convulsion, drowsiness and headache. Meningeal irritation sign was noticed in 80.95vo of cases.
4. Tuberculin test revealed positive reaction in 72.1% of cases.
5. Clinical stage on admission revealed 35 cases of stage I . 1 cases (2.9%) died and 30 cases (85.7%) recovered. Stage j was 32 cases and 6 cases (18.8%) died and 14 cases (43.8 %) recovered. Stage j was 22 cases and 7 cases (31.8%) died and only 3 cases (13.6%)
recovered. Overall mortality was 15.7%.
6. Family history of tuberculosis was found in 29 cases (32.55vo).
7. Chest X-ray revealed tuberculous lesions in 59.5% of all cases and miliary tuberculosis were found. in 20.2% of all cases. j
8. Mean leukocyte count in the cerebrospinal fluid was 261/mm¢¥ and 80.2% of all cases were in the range of 50^500/mm¢¥, In 75.3% of all cases, differential count of lymphocyte was over 75%. Mean protein level in the cerebrospinal fluid was 170mg% and 91.5% of all cases were in the range of 50-300mg%. Sugar level in the cerebrospinal fluid was decreased below 40mg% in the 73.2% of all cases and the mean was 31.7mg%. Mean chloride level was 112.1mEq/1 and 93.1% of all cases were below 120mEq/l.
9. Mortality rate was slightly lower in the group treated with triple therapy and cortico-L steroid than the
group treated with only INH, PAS and SM.
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